Journal :   Asian Journal of Research in Chemistry

Volume No. :   1

Issue No. :  1

Year :  2008

Pages :   51-52

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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New Spectrophotometric Determination of Cefaclor in Bulk Drug and Synthetic Mixture



Address:   Nagori BP and Shukla Shiv Shankar*
Lachoo Memorial College of Sciences and Technology (Pharmacy Wing), Jodhpur-342003 Rajasthan
*Corresponding Author
DOI No:

ABSTRACT:
A simple, economic and reproducible spectroscopic method has been developed for the determination of cefaclor API and in its pharmaceutical formulations. The spectroscopic method is based on the formation of complex with p–di methyl amino benzaldehyde reagent having absorbance maxima at 484.4 nm. Optimization of reaction was carried out with the factors: buffer strength, reaction time, stability of complex, molar ratio of drug: reagent. The Beer-Lambert’s law was followed in the range of 2.5-15 µg/ml.
KEYWORDS:
Cefaclor, Spectrophotometry, p –di methyl amino benzaldehyde reagent.
Cite:
Nagori BP, Shukla Shiv Shankar. New Spectrophotometric Determination of Cefaclor in Bulk Drug and Synthetic Mixture. Asian J. Research Chem. 1(1): July-Sept. 2008;Page 51-52.
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