Journal :   Asian Journal of Research in Chemistry

Volume No. :   1

Issue No. :  1

Year :  2008

Pages :   12-14

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Biological Activity of Some (2E)-Substituted-2-Ethylidene-5,6- Diphenylimidazo[2,1-b][1,3]Thiazol-3-(2H)-Ones

Address:   Bhaskar VH*1, Kumar M2, Balakrishnan BR2 and Sangameswaran B2
1M.P. Patel College of Pharmacy, Kapadwanji, Gujarat- 387 6202.
2Medicinal Plant Research Centre, Vinayaka Mission’s College of Pharmacy, Vinayaka Missions University, Salem 636 008 Tamil Nadu, India.
*Corresponding Author

Certain (2E)-substituted-2-ethylidene-5,6-diphenylimidazo[2,1-b][1,3]thiazol-3-(2H)-ones (4a-f) have been synthesized by the condensation of 4,5-diphenylimidazoin-2-thiones (3) with different aromatic aldehydes and chloroacetic acid in presence of acetic anhydride, anhydrous sodium acetate and glacial acetic acid. These compounds were characterized by their analytical and spectral data. The title compounds were found to be efficient antibacterial agents on evaluation.
Imidazothiazole, Biological Activity, Antibacterial Activity.
Bhaskar VH, Kumar M, Balakrishnan BR, Sangameswaran B. Biological Activity of Some (2E)-Substituted-2-Ethylidene-5,6- Diphenylimidazo[2,1-b][1,3]Thiazol-3-(2H)-Ones. Asian J. Research Chem. 1(1): July-Sept. 2008;Page 12-14.
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