Journal :   Asian Journal of Research in Chemistry

Volume No. :   1

Issue No. :  1

Year :  2008

Pages :   26-28

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Spectrophotometric Methods for Simultaneous Estimation of Rabeprazole and Diclofenac from Combined Tablet Dosage Form



Address:   RW Lohe*1, PB Suruse1 , MK Kale1 , PR Barethiya2 , AV Kasture2 and SW Lohe3
1Kamla Nehru College of Pharmacy, Butibori, Nagpur-441108 (MS) India.
2Institute of Pharmaceutical Education and Research, Borgaon (Meghe) Wardha- 442001 (MS) India.
3Anurag College of Pharmacy, Warthi, Bhandara (MS) India.
*Corresponding Author
DOI No:

ABSTRACT:
Two simple, accurate, economical and reproducible spectrophotometric methods for simultaneous estimation of Rabeprazole and Diclofenac in combined tablet dosage form have been developed. The first developed method employs formation and solving of simultaneous equation using two wavelengths 294.0 nm and 281.2 nm for formation of simultaneous equation. Second developed method involves graphical absorbance ratio, using two wavelengths. Both of these methods obey Beer’s law in the employed concentration ranges for respective methods. Results of analysis were validated statistically and by recovery studies.
KEYWORDS:
Spectrophotometric estimation, Rabeprazole, and Diclofenac.
Cite:
RW Lohe, PB Suruse, MK Kale, PR Barethiya, AV Kasture SW Lohe. Spectrophotometric Methods for Simultaneous Estimation of Rabeprazole and Diclofenac from Combined Tablet Dosage Form. Asian J. Research Chem. 1(1): July-Sept. 2008;Page 26-28.
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