Journal :   Asian Journal of Research in Chemistry

Volume No. :   2

Issue No. :  2

Year :  2009

Pages :   168-170

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Development of UV Spectrophotometric method of Idebenone in Bulk and Pharmaceutical Formulation.



Address:   Amit Rathi*, Dinesh Dhamecha, Saifee Maria and Mohd Hassan G Dehghan
Y.B.Chavan College of Pharmacy ,Dr. Rafiq Zakaria Campus, Maulana Azad Education Trust, Rauza Bagh , Aurangabad (MS) India. 431001
*Corresponding Author
DOI No:

ABSTRACT:
The present research work discusses the development of a UV estimation method for Idebenone. Simple, accurate, cost efficient and reproducible spectrophotometric method has been developed for the estimation of Idebenone in bulk and pharmaceutical dosage form. UV spectrophotometric method, which is based on measurement at maximum wavelength (?max) 282nm. The percentage recovery of Idebenone ranged from 99.68 to 99.82% in pharmaceutical dosage form. Beers law was obeyed in the concentration range of 4-20µg/ml having line equation y = 0.0485x - 0.0239 with correlation coefficient of 0.9978. Results of the analysis were validated statistically and by recovery study.
KEYWORDS:
spectrophotometry, Idebenone.
Cite:
Amit Rathi, Dinesh Dhamecha, Saifee Maria, Mohd Hassan G Dehghan. Development of UV Spectrophotometric method of Idebenone in Bulk and Pharmaceutical Formulation. Asian J. Research Chem. 2(2): April.-June, 2009 page 168-170.
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