Journal :   Asian Journal of Research in Chemistry

Volume No. :   2

Issue No. :  2

Year :  2009

Pages :   104-107

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Method Development and Validation for estimation of Trihexyphenedyl Hydrochloride in Tablet Dosage Forms



Address:   Ashwin Patel1*, Alankar Shrivastava2, Anurekha Jain2 and GK Singh3
1Research Associate, B.A. Research House, Opposite Pushpraj Towers, Near Judges bunglows, Ahmedabad- 380054
2B.R. Nahata College of Pharmacy, Mhu-Neemuch Road, Mandsaur (M.P)-458001
3Lachoo College of Science and Technology, Shastri Nagar, sector A, Jodhpur (Rajasthan)
*Corresponding Author
DOI No:

ABSTRACT:
The development and validation of Trihexyphenidyl Hydrochloride was carried out by Ion pair extraction method. The estimation was measure at 410 nm. Against blank preparation and calibration curve was plotted. The Beer’s Law was linear in concentration range of 2?g/ml to 18 ?g/ml at 410 nm. The method developed was validated to determine its accuracy, precision and specificity. The recovery study was carried out by standard addition method.
KEYWORDS:
Trihexyphenidyl Hydrochloride, Ion pair extraction method , bromocresol green.
Cite:
Ashwin Patel, Alankar Shrivastava, Anurekha Jain, GK Singh. Method Development and Validation for estimation of Trihexyphenedyl Hydrochloride in Tablet Dosage Forms. Asian J. Research Chem. 2(2): April.-June, 2009 page 104-107.
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