Journal :   Asian Journal of Research in Chemistry

Volume No. :   2

Issue No. :  3

Year :  2009

Pages :   273-274

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Potassium Ferricynide and Ferric Chloride: A Chromogenic Reagent for Estimation of Tranexamic Acid by Spectrophotometry



Address:   1Mohite PB*, 1Pandhare RB, 1Khanage SG and 2Bhaskar VH
1M.E.S. College of Pharmacy, Sonai, Ahmednagar, Maharashtra-414105 India
2MP Patel College of Pharmacy, Kapadwanj ,Gujarat India
*Corresponding
DOI No:

ABSTRACT:
A simple, accurate and reproducible spectrophotometric method has been developed for the estimation of Tranexamic acid in bulk and pharmaceutical dosage formulations. The developed method is based on the formation of condensation product of drug with ferric chloride and potassium ferricynide, which shows absorbance maximum at 710 nm. The proposed method showed linearity in the range of 2-20 ug/ml. Results were statistically validated and were found to be reproducible. Recovery studies indicate that the method is accurate.
KEYWORDS:
Tranexamic acid, Ferric chloride, Potassium Ferricynide, Spectrophotometric method.
Cite:
Mohite PB, Pandhare RB, Khanage SG, Bhaskar VH. Potassium Ferricynide and Ferric Chloride: A Chromogenic Reagent for Estimation of Tranexamic Acid by Spectrophotometry. Asian J. Research Chem. 2(3): July-Sept. 2009 page 273-274.
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