Journal : Asian Journal of Research in Chemistry
Volume No. : 2
Issue No. : 3
Year : 2009
Pages : 285-288
ISSN Print : 0974-4169
ISSN Online : 0974-4150
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Address:
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BS Vikram*, T Srinivas Rao and K Ramesh
Karnataka College of Pharmacy, 33/2, Thirumenahalli,Hegde Nagar Main Road,Yelahanka Hobli, Jakkur Post, Bangalore-560064 India
*Corresponding Author
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DOI No:
ABSTRACT:
Pyrazoline derivatives are found to be chemotherapeutically active and they are found to possess anti-inflammatory, anti-bacterial, anti-viral and analgesic activities. The objective of the dissertation work is to synthesize and characterization of 3,5-di-substituted pyrazolines and also to study their anti-bacterial activities.The method followed to synthesize 3,5 di-substituted pyrazolines are as follows: The results have shown that the 3,5 di-substituted pyrazoline derivatives are found to be effective anti-bacterial agents. The synthesized compounds were elucidated by spectral data. By analysis of IR, NMR and MASS spectral data the compounds reveals the successful information of 3,5-di-substituted pyrazolines and also about different aromatic groups at position 3 and 5.The synthesized compounds were screened for their anti-bacterial activities by using standard as ampicilin and are found to be effective chemotherapeutic agent. The synthesis of pyrazolines by the described methods resulted in the products with good yield.
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KEYWORDS:
Chalcones, pyrazolines, Heterocyclic compound, Anti-bacterial.
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Cite:
BS Vikram, T Srinivas Rao, K Ramesh. Synthesis and in Vitro Antimicrobial Activity of some New 3, 5 di-substituted pyrazoline derivatives. Asian J. Research Chem. 2(3): July-Sept., 2009, page 285-288.
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