Journal :   Asian Journal of Research in Chemistry

Volume No. :   2

Issue No. :  3

Year :  2009

Pages :   285-288

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis and in Vitro Antimicrobial Activity of some New 3, 5 di-substituted pyrazoline derivatives



Address:   BS Vikram*, T Srinivas Rao and K Ramesh
Karnataka College of Pharmacy, 33/2, Thirumenahalli,Hegde Nagar Main Road,Yelahanka Hobli, Jakkur Post, Bangalore-560064 India
*Corresponding Author
DOI No:

ABSTRACT:
Pyrazoline derivatives are found to be chemotherapeutically active and they are found to possess anti-inflammatory, anti-bacterial, anti-viral and analgesic activities. The objective of the dissertation work is to synthesize and characterization of 3,5-di-substituted pyrazolines and also to study their anti-bacterial activities.The method followed to synthesize 3,5 di-substituted pyrazolines are as follows: The results have shown that the 3,5 di-substituted pyrazoline derivatives are found to be effective anti-bacterial agents. The synthesized compounds were elucidated by spectral data. By analysis of IR, NMR and MASS spectral data the compounds reveals the successful information of 3,5-di-substituted pyrazolines and also about different aromatic groups at position 3 and 5.The synthesized compounds were screened for their anti-bacterial activities by using standard as ampicilin and are found to be effective chemotherapeutic agent. The synthesis of pyrazolines by the described methods resulted in the products with good yield.
KEYWORDS:
Chalcones, pyrazolines, Heterocyclic compound, Anti-bacterial.
Cite:
BS Vikram, T Srinivas Rao, K Ramesh. Synthesis and in Vitro Antimicrobial Activity of some New 3, 5 di-substituted pyrazoline derivatives. Asian J. Research Chem. 2(3): July-Sept., 2009, page 285-288.
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