Journal :   Asian Journal of Research in Chemistry

Volume No. :   2

Issue No. :  4

Year :  2009

Pages :   411-413

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis and Biological Screening of Novel Aminoalkyl Substituted Azaphenothiazine

Address:   P. Valentina*, K. Ilango, Deepak Jain and Prerna Shukla
Department of Pharmaceutical Chemistry, SRM College of Pharmacy, SRM University, Kattankulathur - 603 203
*Corresponding Author

Some novel series of alkyl substituted azaphenothiazine were synthesized by condensation of 2-chloro-1-(10H-azaphenothiazin-10yl) ethanone with various amines. The synthesized compounds were confirmed by IR, 1HNMR and Mass spectroscopy.. The bioavailabilities of the compounds were determined by Lipinski rule of 5 using customized software. All the compounds were screened for antimicrobial and sedative activity.
Azaphenothiazine, Bioavailability, Antimicrobial activity, Sedative activity.
P. Valentina, K. Ilango, Deepak Jain, Prerna Shukla. Synthesis and Biological Screening of Novel Aminoalkyl Substituted Azaphenothiazine. Asian J. Research Chem. 2(4):Oct.-Dec. 2009 page 411-413.
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