Journal :   Asian Journal of Research in Chemistry

Volume No. :   2

Issue No. :  4

Year :  2009

Pages :   411-413

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis and Biological Screening of Novel Aminoalkyl Substituted Azaphenothiazine



Address:   P. Valentina*, K. Ilango, Deepak Jain and Prerna Shukla
Department of Pharmaceutical Chemistry, SRM College of Pharmacy, SRM University, Kattankulathur - 603 203
*Corresponding Author
DOI No:

ABSTRACT:
Some novel series of alkyl substituted azaphenothiazine were synthesized by condensation of 2-chloro-1-(10H-azaphenothiazin-10yl) ethanone with various amines. The synthesized compounds were confirmed by IR, 1HNMR and Mass spectroscopy.. The bioavailabilities of the compounds were determined by Lipinski rule of 5 using customized software. All the compounds were screened for antimicrobial and sedative activity.
KEYWORDS:
Azaphenothiazine, Bioavailability, Antimicrobial activity, Sedative activity.
Cite:
P. Valentina, K. Ilango, Deepak Jain, Prerna Shukla. Synthesis and Biological Screening of Novel Aminoalkyl Substituted Azaphenothiazine. Asian J. Research Chem. 2(4):Oct.-Dec. 2009 page 411-413.
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