Journal :   Asian Journal of Research in Chemistry

Volume No. :   2

Issue No. :  4

Year :  2009

Pages :   432-433

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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UV Spectrophotometric Method Development for the Determination of Domperidone in Tablet Formulation



Address:   Kailash Nath Kaushik and Saurabh Kumar Banerjee *
School of Pharmacy Technology and Management, SVKM’s, NMIMS University, Shirpur Campus, Shirpur, Dist: Dhule (M.S), India 425 405
*Corresponding Author
DOI No:

ABSTRACT:
A simple, accurate, precise and reproducible method for the estimation of domperidone (DOM) in tablet dosage form was developed utilizing concept of UV spectrophotometry. Methanol was used as the solvent for domperidone. The UV spectrum of domperidone in methanol showed ? max at 287.5 nm and Beer-Lambert law was obeyed in the concentration range of 6-36 µg/ml. Wavelength selected for estimation of domperidone was 287.5 nm. The result of analysis has been validated statistically. The recovery studies range from 99.5 to 100.1% confirmed the accuracy of the proposed methods.
KEYWORDS:
Domperidone, UV spectrophotometry.
Cite:
Kailash Nath Kaushik, Saurabh Kumar Banerjee. UV Spectrophotometric Method Development for the Determination of Domperidone in Tablet Formulation. Asian J. Research Chem. 2(4):Oct.-Dec. 2009 page 432-433.
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