Journal :   Asian Journal of Research in Chemistry

Volume No. :   2

Issue No. :  4

Year :  2009

Pages :   369-375

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Apoptosis Significance and Molecular Mechanisms- A Review



Address:   Merlin NJ*1, Parthasarathy V1, Manavalan R1, Devi P2 and Meera R2
1Annamalai University, Annamalai Nagar, Tamil Nadu, India Pincode-608002
2K.M.College of Pharmacy, Uthangudi, Madurai, Tamilnadu, India. Pincode- 625107
*Corresponding Author
DOI No:

ABSTRACT:
Apoptosis, a form of programmed cell death, is a pivotal defense against the occurrence of cancer and is essential to metazoans in maintaining tissue homeostasis. Apoptosis exhibits a distinctive phenotype and involves elimination of potentially deleterious cells. Many diseases have been associated with aberrantly regulated apoptotic cell death, ultimately leading to inhibition of apoptosis and propagation of diseases such as cancer. This review highlights the significance of apoptosis, molecular mechanisms of apoptosis and various methods of causing cell death.
KEYWORDS:
Apoptosis, programmed cell death, significance, mechanisms, caspases, Bcl-2 family.
Cite:
Merlin NJ Parthasarathy V, Manavalan R, Devi P, Meera R. Apoptosis Significance and Molecular Mechanisms- A Review. Asian J. Research Chem. 2(4):Oct.-Dec. 2009 page 369-375.
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