Journal :   Asian Journal of Research in Chemistry

Volume No. :   2

Issue No. :  4

Year :  2009

Pages :   472-475

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Microwave-Assisted Synthesis and Antibacterial Activity of Some New Flavones and 1, 5-Benzothiazepines



Address:   VA Navale, SS Mokle, Archana Y Vibhute, KG Karamunge, SV Khansole, SB Junne and YB Vibhute*
P.G. Department of Chemistry, Yeshwant Mahavidyalaya, Nanded 431602 (M.S.) INDIA
*Corresponding Author
DOI No:

ABSTRACT:
The synthesis of heterocyclic compounds containing flavones (4a-i) and 1,5-benzothiazepines(5a-i) from chalcone derivatives containing 3,4-methylenedioxy phenyl ring using microwave irradiation in 80-97% yield within 2 – 4 min. The work-up is simple, shorter reaction time, increase in reaction rate with better yields. The structures of synthetic compounds have been characterized using IR and 1H NMR spectral data together with halogen analysis. All synthesized compounds have been screened for their antibacterial activity.
KEYWORDS:
Chalcones, flavones, 1,5-benzothiazepines, microwave irradiation, antibacterial activity.
Cite:
VA Navale, SS Mokle, Archana Y Vibhute, KG Karamunge, SV Khansole, SB Junne, YB Vibhute. Microwave-Assisted Synthesis and Antibacterial Activity of Some New Flavones and 1, 5-Benzothiazepines.Asian J. Research Chem. 2(4):Oct.-Dec. 2009 page 472-475.
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