Journal :   Asian Journal of Research in Chemistry

Volume No. :   2

Issue No. :  4

Year :  2009

Pages :   513-515

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis and Biological Evaluation of New Benzothiazole Derivatives



Address:   Vrushali N Patil, Ameya Yadav, AS Bobade*, SV Athlekar, LS Patil and Abhay Chowdhary
Department of Chemotherapy, Haffkine Institute for Training, Research and Testing, Parel, Mumbai- 400012
DOI No:

ABSTRACT:
A series of 2-N-acetyl-[2’-(thieno substituted aryl ketone)-5’-methyl-1’,3’,4’-oxadiazolyl] benzothiazole (5a-e) have been synthesized. These structures are determined by the elemental analysis and spectral data (IR, 1H-NMR). These new derivatives are evaluated for in vitro antimicrobial activity against Staphylococcus aureus ATCC 3750, Salmonella typhi NCTC 786, Candida albicans ATCC 10231 and Aspergillus niger ATCC 16404.
KEYWORDS:
2-amino benzothiazole, 1,3,4-oxadiazole, anti–bacterial, anti–fungal.
Cite:
Vrushali N Patil, Ameya Yadav, AS Bobade, SV Athlekar, LS Patil, Abhay Chowdhary. Synthesis and Biological Evaluation of New Benzothiazole Derivatives. Asian J. Research Chem. 2(4):Oct.-Dec. 2009 page 513-515.
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