Journal :   Asian Journal of Research in Chemistry

Volume No. :   2

Issue No. :  4

Year :  2009

Pages :   553-555

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Simple Validated Spectroscopic Method for Estimation of Amlodipine Besylate from Tablet Formulation



Address:   Pallavi Salve*, Deepali Gharge, Rupali Kirtawade, Pandurang Dhabale, Kishor Burade
Government College of Pharmacy, Karad, Dist –Satara-415124, M.S., India
*Corresponding Author
DOI No:

ABSTRACT:
Amlodipine Besylate is a Calcium channel blocker, anti-hypertensive agent. Various methods for analysis of the same are available but are time consuming and expensive. Here we have developed a new, precise and simple UV spectrophotometric method for estimation of Amlodipine Besylate from tablet formulation. The drug obeyed the Beer’s law and showed good correlation. Absorption maxima of Amlodipine in double distilled water was found to be at 239 nm. Beer’s law was obeyed in concentration range 2 – 12 mcg/ml. The results of analysis were validated by recovery studies. The recovery was more than 99%. The method was found to be simple, accurate, precise, economical and robust.
KEYWORDS:
Amlodipine Besylate, UV spectrophotometry, Recovery, Accuracy.
Cite:
Pallavi Salve, Deepali Gharge, Rupali Kirtawade, Pandurang Dhabale, Kishor Burade. Simple Validated Spectroscopic Method for Estimation of Amlodipine Besylate from Tablet Formulation. Asian J. Research Chem. 2(4):Oct.-Dec. 2009 page 553-555.
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