Journal :   Asian Journal of Research in Chemistry

Volume No. :   3

Issue No. :  1

Year :  2010

Pages :   1-4

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthon Approach in Designing Organic Synthesis

Address:   A. A. Kulkarni1*, S. R. Doshi1, R. K. Nanda1 and N. R. Chatterjee2
1Pad. Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune-411018, Maharashtra
2Dr. D.Y. Patil College of Pharmacy, Akurdi, Pune-411044, Maharashtra, India
*Corresponding Author

Synthon approach is a very useful analytical tool. It is an analytical approach to Organic Synthesis in which the target molecule is broken into fragments through a series of logical disconnection to get the best plausible and likely starting materials (ie.synthons or building blocks) for the target molecule. Synthesis is the real test of the organic medicinal chemist to use and control organic reactions. In each case the starting material is converted to some desired compound, the target molecule through some key intermediate. Actually, a number of synthetic routes can be written for a given target molecule. But in actual synthesis, generally that route is selected which is economical, safe, and easy to carry out and produces maximum yield in a short reaction time.
Synthon approach, Synthon, Disconnection rules.
A. A. Kulkarni, S. R. Doshi, R. K. Nanda, N. R. Chatterjee. Synthon Approach in Designing Organic Synthesis. Asian J. Research Chem. 3(1):Jan.-Mar. 2010 page 1-4.
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