Journal :   Asian Journal of Research in Chemistry

Volume No. :   3

Issue No. :  1

Year :  2010

Pages :   142-144

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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New Simple UV Spectrophotometric Method for Estimation of Almotriptan Malate in Bulk and Pharmaceutical Dosage Forms



Address:   A Suneetha1 and B Syama Sundar2*
1Department of Pharmaceutical Analysis, Hindu College of Pharmacy, Amaravathi Road, Guntur 522 002
2Department of Chemistry / Pharmacy, Acharya Nagarjuna University, Nagarjuna Nagar, Guntur 522 510
*Corresponding Author
DOI No:

ABSTRACT:
A new simple, sensitive, precise, accurate and economical UV spectrophotometric method of analysis for almotriptan malate both as a bulk drug and in tablet formulations was developed and validated. The method employed methanol as solvent and the drug shows maximum absorbance at 227 nm with molar absorptivity of 0.8532×105 L/mol.cm. The linear regression analysis data for the calibration plot showed good linear relationship with r2 = 0.9999 in the concentration range of 1-5 µg/ml. Results of analysis were validated statistically and by recovery studies
KEYWORDS:
Almotriptan malate, U.V spectrophotometry, tablets.
Cite:
A Suneetha, B Syama Sundar. New Simple UV Spectrophotometric Method for Estimation of Almotriptan Malate in Bulk and Pharmaceutical Dosage Forms. Asian J. Research Chem. 3(1): Jan.-Mar. 2010; Page 142-144.
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