Journal :   Asian Journal of Research in Chemistry

Volume No. :   3

Issue No. :  1

Year :  2010

Pages :   151-153

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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UV Spectrophotometric Determination of Risperidone in Bulk and Its Formulation



Address:   Kathirvel S1*, Devala Rao G2 and Satyanarayana SV3
1Dept. of Pharmaceutical Analysis, Hindu College of Pharmacy, Amaravathi Road, Guntur-2, A.P, India
2Dept. of Pharmaceutical Analysis, KVSR Siddhartha College of Pharmacy, Vijayawada-10, A.P, India.
NTU College of Engineering, Anantapur-515002, A.P, India
*Corresponding Author
DOI No:

ABSTRACT:
A simple, sensitive and economical UV spectrophotometric method has been developed for the determination of Risperidone in bulk and tablet dosage forms. Risperidone is an anti-psychotic drug, which shows maximum absorbance at 238nm in 0.1N HCl. Beer’s law was obeyed in the concentration range of 5-30 µg/ml with correlation coefficient of 0.9999.The standard plot clearly showed a straight line passing through the origin. The results of analysis were validated statistically and by recovery studies and found to be satisfactory. The proposed method was extended to pharmaceutical formulations and there was no interference of additives and excipients.
KEYWORDS:
Risperidone; UV Spectrophotometric; tablet dosage form.
Cite:
Kathirvel S, Devala Rao G, Satyanarayana SV. UV Spectrophotometric Determination of Risperidone in Bulk and Its Formulation. Asian J. Research Chem. 3(1): Jan.-Mar. 2010; Page 151-153.
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