Journal :   Asian Journal of Research in Chemistry

Volume No. :   3

Issue No. :  1

Year :  2010

Pages :   161-165

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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An Efficient One Pot Synthesis of Substituted Derivatives of Pyrimido Benzothiazole



Address:   Vijay N Bhosale1*, Sambhaji P Vartale1, Sarla N Kalyankar1, Jagannath S Jadhav2 and Sharad V Kuberkar1
1P. G. Department of Organic Chemistry, Yeshwant Mahavidyalaya, Nanded- 431602,India
2Department of Organic Chemistry, N.S.B. College, Nanded-431605,India
*Corresponding Author
DOI No:

ABSTRACT:
8-Chloro–3- cyano – 2 - methylthio – 4 - oxo - 4[H] - pyrimido - [2,1-b] [1,3] benzothiazole has been prepared by the reaction of 6-Chloro-2-amino benzothiazole with ethyl-2-cyano-3,3-bismethylthioacrylate in the presence of diemethyl formamide and anhydrous potassium carbonate. Suspectibility of compound towards condensation with different reagents like aryl amines, heteryl amines, phenols and compound containing active methylene group has been investigated.
KEYWORDS:
8-Chloro–3- cyano – 2 - methylthio – 4 - oxo - 4[H] - pyrimido - [2, 1-b] [1, 3] benzothiazole, ethyl-2-cyano-3, 3-bismethylthioacrylate.
Cite:
Vijay N Bhosale, Sambhaji P Vartale, Sarla N Kalyankar, Jagannath S Jadhav, Sharad V Kuberkar. An Efficient One Pot Synthesis of Substituted Derivatives of Pyrimido Benzothiazole. Asian J. Research Chem. 3(1):Jan.-Mar. 2010 page 161-165.
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