Journal :   Asian Journal of Research in Chemistry

Volume No. :   3

Issue No. :  1

Year :  2010

Pages :   22-25

ISSN Print :  0974-4169

ISSN Online :  0974-4150


Registration

Allready Registrered
Click to Login

Synthesis and Evaluation of Pyrrole Derivative Conjugates of Aspirin as Anti-Platelet Agents



Address:   Saurabh Chaturvedi*1, Rakesh Saini1, AN Kesari1, Awani Rai1, Neelotma Maurya1 and M ShaharYar2
1Pranveer Singh Institute of Technology, Bhauti, Kanpur, (U.P) India, 208020
2Jamiya Hamdard University, New Delhi, India
*Corresponding Author
DOI No:

ABSTRACT:
A new series of NSAID’S in which aspirin is joined by ester linkage to pyrrole-2-carboxylic acid were synthesized and tested for anti-platelet activity. Related propyl esters of aspirin and aspirin as such were taken as references. All the compounds described here show anti-platelet activity but they do not behave as prodrugs of aspirin in blood serum.
KEYWORDS:
NSAID’S, Aspirin, Anti-Platelet Agents, Pyrrole.
Cite:
Saurabh Chaturvedi, Rakesh Saini, AN Kesari, Awani Rai, Neelotma Maurya, M ShaharYar. Synthesis and Evaluation of Pyrrole Derivative Conjugates of Aspirin as Anti-Platelet Agents. Asian J. Research Chem. 3(1):Jan.-Mar. 2010 page 22-25.
[View HTML]      [View PDF]



Visitor's No. :   126925