Journal : Asian Journal of Research in Chemistry
Volume No. : 3
Issue No. : 1
Year : 2010
Pages : 22-25
ISSN Print : 0974-4169
ISSN Online : 0974-4150
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Saurabh Chaturvedi*1, Rakesh Saini1, AN Kesari1, Awani Rai1, Neelotma Maurya1 and M ShaharYar2
1Pranveer Singh Institute of Technology, Bhauti, Kanpur, (U.P) India, 208020
2Jamiya Hamdard University, New Delhi, India
*Corresponding Author
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DOI No:
ABSTRACT:
A new series of NSAID’S in which aspirin is joined by ester linkage to pyrrole-2-carboxylic acid were synthesized and tested for anti-platelet activity. Related propyl esters of aspirin and aspirin as such were taken as references. All the compounds described here show anti-platelet activity but they do not behave as prodrugs of aspirin in blood serum.
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KEYWORDS:
NSAID’S, Aspirin, Anti-Platelet Agents, Pyrrole.
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Cite:
Saurabh Chaturvedi, Rakesh Saini, AN Kesari, Awani Rai, Neelotma Maurya, M ShaharYar. Synthesis and Evaluation of Pyrrole Derivative Conjugates of Aspirin as Anti-Platelet Agents. Asian J. Research Chem. 3(1):Jan.-Mar. 2010 page 22-25.
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