Journal :   Asian Journal of Research in Chemistry

Volume No. :   3

Issue No. :  2

Year :  2010

Pages :   335-338

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis and Antimicrobial Activity of 5-Substituted-2-(1-H-Benzimidazole) Sulfonamides



Address:   YS Rane, RR Varma, LS Patil, SV Athlekar, AS Chowdhary and AS Bobade*
Department of Chemotherapy, Haffkine Institute for Training, Research and Testing, Parel Mumbai -12
*Corresponding Author
DOI No:

ABSTRACT:
Heterocyclic compounds such as 5-substituted-2-(1-H-benzimidazole) sulfonamides were synthesized by condensation of 5-substituted-2-(1-H-benzimidazole)-sulfonyl chloride and 2-aminoheterocycles with triethyl amine in dry acetone. The synthesized compounds were checked for their antimicrobial potency by screening them against two bacterial strains as well as one fungal strain. The structures of compounds have been established on the basis of their elemental analysis and spectral data.
KEYWORDS:
Sulphonamides, 2-mercapto benzimidazole, antifungal, antibacterial.
Cite:
YS Rane, RR Varma, LS Patil, SV Athlekar, AS Chowdhary, AS Bobade. Synthesis and Antimicrobial Activity of 5-Substituted-2-(1-H-Benzimidazole) Sulfonamides. Asian J. Research Chem. 3(2): April- June 2010; Page 335-338.
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