Journal :   Asian Journal of Research in Chemistry

Volume No. :   3

Issue No. :  3

Year :  2010

Pages :   528-530

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Free Radical Scavenging Activity of Novel 5-Substituted Arylidene-3-Substituted-Benzyl-Thiazolidine-2, 4-Diones



Address:   Ankush Garg, Radhika Maheshwari, Pooja Chawla* and Shubhini A. Saraf
Faculty of Pharmacy, Babu Banarasi Das National Institute of Technology and Management, Dr. Akhilesh Das Nagar, Sector 1, Faizabad Road, Lucknow Pin 227105 (UP), India *Corresponding Author
DOI No:

ABSTRACT:
A series of 5-substituted-arylidene-3-substituted-benzyl-thiazolidine-2, 4-dione derivatives were synthesized from thaizolidinedione and substituted benzyl chloride followed by the addition of substituted aromatic aldehydes. All the compounds 1(a)-1(e) and 2(a)-2(c) were screened for their in vitro antioxidant activity using DPPH method. The anisaldehyde based thiazolidinedione compounds 1(a) and 2(a) displayed good activity comparable to those of standard.
KEYWORDS:
Thiazolidine-2, 4-dione, Heterocyclic compounds, Antioxidant activity.
Cite:
Ankush Garg, Radhika Maheshwari, Pooja Chawla, Shubhini A. Saraf. Free Radical Scavenging Activity of Novel 5-Substituted Arylidene-3-Substituted-Benzyl-Thiazolidine-2, 4-Diones. Asian J. Research Chem. 3(3): July- Sept. 2010; Page 528-530.
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