Journal :   Asian Journal of Research in Chemistry

Volume No. :   3

Issue No. :  3

Year :  2010

Pages :   604-607

ISSN Print :  0974-4169

ISSN Online :  0974-4150


Registration

Allready Registrered
Click to Login

Method Development and Validation for Estimation of Quetiapine Fumarate by RP-HPLC



Address:   Ashish Baldi*, Ashutosh Kumar Patidar and Jyotsana SanadyA
College of Pharmacy, Shri R.M.S. Institute of Science and Technology, Bhanpura, Dist. Mandsaur, (M. P.) 458775 India
*Corresponding Author
DOI No:

ABSTRACT:
A precise and accurate reverse phase high-performance liquid chromatographic (RP-HPLC) method was developed and validated for estimation of quetiapine fumarate. The mobile phase consisted of methanol: water: acetonitrile (50: 40:10) was used at a flow rate of 1 ml/min and pH value of 7.0, adjusted with orthophosphosphoric acid. The detection was carried out at a wavelength of 251 nm. The developed method was found to be in accordance with ICH guidelines with respect to accuracy, precision, reproducibility, linearity and specificity.
KEYWORDS:
Quetiapine fumarate, RP-HPLC, Validation.
Cite:
Ashish Baldi, Ashutosh Kumar Patidar, Jyotsana SanadyA. Method Development and Validation for Estimation of Quetiapine Fumarate by RP-HPLC. Asian J. Research Chem. 3(3): July- Sept. 2010; Page 604-607.
[View HTML]      [View PDF]



Visitor's No. :   127816