Journal :   Asian Journal of Research in Chemistry

Volume No. :   3

Issue No. :  3

Year :  2010

Pages :   707-709

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Simultaneous Spectrophotometric Determination of Lamivudine and Abacavir in the Mixture



Address:   V.P. Devmurari*
Smt. R B Patel Mahila Pharmacy College, Kailshnagar, Bhavnagar road, Atkot 360040.Dist: Rajkot, Gujarat
*Corresponding Author
DOI No:

ABSTRACT:
A novel, simple, rapid and sensitive spectrophotometer method has been developed for simultaneous estimation of Lamivudine and Abacavir. The method employs formation and solving of simultaneous equation using 280 nm and 297 nm as two analytical wavelengths. Both the drugs obey Beer’s Law in the concentration ranges employed for this method. Accuracy and reproducibility of the proposed method was statistically validated by recovery studies. The method is found to be rapid, precise and accurate and can easily be employed in the laboratory for the routine estimation of drugs.
KEYWORDS:
Lamivudine, abacavir, Spectrophotometric estimation, UV-Visible ectrophotometer.
Cite:
V.P. Devmurari. Simultaneous Spectrophotometric Determination of Lamivudine and Abacavir in the Mixture. Asian J. Research Chem. 3(3): July- Sept. 2010; Page 707-709.
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