Journal :   Asian Journal of Research in Chemistry

Volume No. :   3

Issue No. :  3

Year :  2010

Pages :   714-715

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Spectrophotometric Estimation of Tramadol Hydrochloride in Bulk and Tablet Dosage Form



Address:   S.R. Bavaskar*, A.D. Agrawal, Y.S. Agrawal, A.N. Amrutkar, Niraj L. Badhe and P.S. Kawatikwar
Shree Sureshdada Jain Institute of Pharmaceutical Education and Research, Jammer Dist-Jalgaon 424206
*Corresponding Author
DOI No:

ABSTRACT:
A simple, sensitive, accurate and precise UV Spectrophotometric method has been developed for quantitative determination of Tramadol Hydrochloride in bulk and tablet formulations. The UV- spectrum was scanned between 220 to 400 nm and 270.5 nm was selected as maximum wavelength for absorption. Tramadol shows molar absorptivity of 1.771×104l/mol/cm and Sandell’s sensitivity 0.16927mcg/Sq.cm/0.001-absorbance units. Beer’s law was obeyed in the concentration range of 15-170 µg/ml. Results of analysis were validated statistically and by recovery studies.
KEYWORDS:
Tramadol hydrochloride, tablet, ultraviolet spectrophotometric estimation.
Cite:
S.R. Bavaskar, A.D. Agrawal, Y.S. Agrawal, A.N. Amrutkar, Niraj L. Badhe, P.S. Kawatikwar. Spectrophotometric Estimation of Tramadol Hydrochloride in Bulk and Tablet Dosage Form. Asian J. Research Chem. 3(3): July- Sept. 2010; Page 714-715.
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