Journal :   Asian Journal of Research in Chemistry

Volume No. :   3

Issue No. :  4

Year :  2010

Pages :   876-878

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Phytochemical Screening and In-vitro Antioxidant Activity of Cissus quadrangualris



Address:   Anitha Jebamalai Raj1 and Sudarsanam Dorairaj2*
1Department of Bioinformatics, Karpagam University, Coimbatore
2Department of Advanced Zoology, Biotechnology and Bioinformatics Unit, Loyola College, Chennai
*Corresponding Author
DOI No:

ABSTRACT:
Cissus quadrangualris is a medicinal herb used in traditional medicine of India as fracture healing process, asthma, cardiac problems, tumor and skin diseases. Cissus quadrangualris stem extracted with five solvents (Petroleum ether, chloroform, ethylacteate, methanol and water). Antioxidant activity of methanol extract of Cissus quadrangualris stem was studied for its free radical scavenging property on in-vitro models: ABTS.+ and Superoxide anion radical scavenging activity comparable with that of reference antioxidant butylated hydroxytoluene (BHT).The extract showed good dose dependent free radical scavenging property in ABTS.+ and Superoxide anion radical scavenging assay. In general, the methanol extract exhibited good antioxidant activity in ABTS.+ and Superoxide anion(81.49?0.03 µg/ml) and (71.19?0.03 µg/ml)but were significantly lower than the synthetic antioxidant (84.230.04 µg/ml) and (79.230.01 µg/ml).The IC50 values of ABTS.+ and Superoxide anion radical scavenging activity were found to be (179.60.03 µg/ml), (1900.04 µg/ml) and that of the standard BHT was (150.00.02 µg/ml) and (173.30.06 µg/ml). Phytochemical Screening disclosed the presence of alkaloids, flavonoids, saponins, terpenoids, steroids, tannins, cardioglycosides, amino acids and proteins. The result suggests that the methanol extracts of Cissus quadrangualris stem have potent antioxidant activity against free radicals.
KEYWORDS:
Cissus quadrangualris, Phytochemical Screening, Antioxidant activity.
Cite:
Anitha Jebamalai Raj, Sudarsanam Dorairaj. Phytochemical Screening and In-vitro Antioxidant Activity of Cissus quadrangualris. Asian J. Research Chem. 3(4): Oct. - Dec. 2010; Page 876-878.
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