Journal :   Asian Journal of Research in Chemistry

Volume No. :   3

Issue No. :  4

Year :  2010

Pages :   935-937

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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A Validated UV Spectrophotometric Method for Estimation of Escitalopram Oxalate in Bulk and Pharmaceutical Dosage Forms


Suneetha A., Syama Sundar B.

profbsyamsundar@yahoo.co.in

Address:   Suneetha A.1 and Syama Sundar B.2*
1Department of Pharmaceutical Analysis, Hindu College of Pharmacy, Amaravathi Road, Guntur (A.P)
2Department of Pharmacy, Acharya Nagarjuna University, Nagarjuna Nagar Guntur (A.P)
*Corresponding Author
DOI No:

ABSTRACT:
A simple, sensitive, precise, accurate and economical spectrophotometric method of analysis for escitalopram oxalate both as a bulk drug and in tablet dosage forms was developed and validated. The method employed methanol as solvent and the drug shows maximum absorbance at 239 nm with molar absorptivity of 0.1742×105 L/mol.cm. The linear regression analysis data for the calibration plot showed good linear relationship with r2 = 0.9999 in the concentration range of 5-25 µg/ml. Results of analysis were validated statistically and by recovery studies.
KEYWORDS:
Escitalopram oxalate, U.V spectrophotometry, tablets.
Cite:
Suneetha A., Syama Sundar B.. A Validated UV Spectrophotometric Method for Estimation of Escitalopram Oxalate in Bulk and Pharmaceutical Dosage Forms. Asian J. Research Chem. 3(4): Oct. - Dec. 2010; Page 935-937.
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