Journal :   Asian Journal of Research in Chemistry

Volume No. :   3

Issue No. :  4

Year :  2010

Pages :   1077-1079

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Ultra-Violet Spectrophotometric Method for Estimation of Azelnidipine from Bulk Drug and Pharmaceutical Formulation


Rele R.V., Patil S.P.

spp30@rediffmail.com

Address:   Rele R.V.* and Patil S.P.
D.G. Ruparel College, Matunga, Mumbai 400 016
*Corresponding Author
DOI No:

ABSTRACT:
A simple, rapid sensitive and precise UV spectrophotometric method has been developed for the estimation of azelnidipine from bulk drug and pharmaceutical formulation. In this method azelnidipine showed maximum absorbance at about 254 nm in methanol. Beer’s law was followed in the concentration range of 1 to 20 µg/ml. Regression equation was found to be y = 0.0478 x + 0.0013 and coefficient of correlation was 0.9999. The proposed method is sensitive, accurate, reproducible and useful for the estimation of azelnidipine from bulk drug and pharmaceutical formulation.
KEYWORDS:
Azelnidipine UV-spectrophotometer Methanol.
Cite:
Rele R.V., Patil S.P.. Ultra-Violet Spectrophotometric Method for Estimation of Azelnidipine from Bulk Drug and Pharmaceutical Formulation. Asian J. Research Chem. 3(4): Oct. - Dec. 2010; Page 1077-1079.
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