Journal :   Asian Journal of Research in Chemistry

Volume No. :   3

Issue No. :  4

Year :  2010

Pages :   1103-1106

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Conventional and Microwave-assisted Synthesis of 5-Halogeno-(X) 2, 4-(1H, 3H) Pyrimidinedione and Their Biological Evaluation



Address:   Shahana Ehsan and Bushra Khan
Chemistry Department, Lahore College for Women University, Jail Road, Lahore, Pakistan
*Corresponding Author
DOI No:

ABSTRACT:
A series of 5-halogen substituted 2, 4-(1H, 3H)Pyrimidinedione compounds have been synthesized by an effective, rapid microwave assisted method. The structures of compounds have been elucidated with UV, FTIR, GC-Mass spectrometer, solubility and melting points of compounds were determined. The antibacterial, antifungal and antiviral screening against B.subtilis, S.aureus, E.coli, A.nigar, A.flavus and ND virus revealed their significant activities.
KEYWORDS:
Pyrimidinedione, Halogenation, Superoxol, Microwave.
Cite:
Shahana Ehsan, Bushra Khan. Conventional and Microwave-assisted Synthesis of 5-Halogeno-(X) 2, 4-(1H, 3H) Pyrimidinedione and Their Biological Evaluation. Asian J. Research Chem. 3(4): Oct. - Dec. 2010; Page 1103-1106.
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