Journal :   Asian Journal of Research in Chemistry

Volume No. :   4

Issue No. :  1

Year :  2011

Pages :   116-119

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis and Antimicrobial Activities of Thiazolo [3, 2-a] Pyrimidine Derivatives

Address:   Monika Bansal, Ramandeep Kaur and Balbir Kaur*
Department of Chemistry, Punjabi University, Patiala-147002 (Punjab) India
*Corresponding Author

In the present study a novel thiazolo [3,2-a] pyrimidines were synthesized by one pot multicomponent cyclocondensation of 2-amino-4-phenyl thiazole, benzoyl acetone and various substituted aromatic aldehydes on solid support under microwave irradiations. The 2-amino-4-phenyl thiazole was synthesized from acetophenone. Some of the compounds were screened for anti-bacterial (Staphylococcus aureus, Staphylococcus aureus (MRSA), Staphylococcus pyogenes) and antifungal (Aspergillus niger, Neurospora crassa) activities by Agar Diffusion method.
Thiazolopyrimidines, Microwave, Silica as solid support, Antimicrobial studies.
Monika Bansal, Ramandeep Kaur, Balbir Kaur. Synthesis and Antimicrobial Activities of Thiazolo [3, 2-a] Pyrimidine Derivatives. Asian J. Research Chem. 4(1): January 2011; Page 116-119.
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