Journal :   Asian Journal of Research in Chemistry

Volume No. :   4

Issue No. :  1

Year :  2011

Pages :   40-43

ISSN Print :  0974-4169

ISSN Online :  0974-4150


Registration

Allready Registrered
Click to Login

Synthesis, Characterization and Antimicrobial Activity of a 5(4-(4-Substituted)Aminobenzylidine)Thiazolidine-2,4-Dione Derivatives



Address:   Suresh Rajput1, Dharamveer Sisodia1, Hemant Badwaik2*, Deepa Thakur2 and Kushagra Nagori2
1Ultra College of Pharmacy, Madurai (T.N)
2Rungta College of Pharmaceutical Sciences and Research, Bhilai (C.G)
*Corresponding Author
DOI No:

ABSTRACT:
A novel 5(4-(4-substituted)Aminobenzylidine)thiazolidine-2,4-dione derivatives were synthesized and characterized by IR and H-NMR spectral analysis. Antibacterial and antifungal activities of the compounds were assessed by in vitro growth inhibitory activity against Escherichia coli, Staphylococcus aureus, Asperigillus niger, Candida albicans by using the disc diffusion method. Most of all compounds exhibited significant antibacterial activity against Staphylococcus aureus and Escherichia coli, while weak antifungal activity against Asperigillus niger and Candida albicans.
KEYWORDS:
Thiazolidine-2,4-dione, Antibacterial and antifungal activity, Disc diffusion method.
Cite:
Suresh Rajput, Dharamveer Sisodia, Hemant Badwaik, Deepa Thakur, Kushagra Nagori. Synthesis, Characterization and Antimicrobial Activity of a 5(4-(4-Substituted)Aminobenzylidine)Thiazolidine-2,4-Dione Derivatives. Asian J. Research Chem. 4(1): January 2011; Page 40-43.
[View HTML]      [View PDF]



Visitor's No. :   106482