Journal :   Asian Journal of Research in Chemistry

Volume No. :   4

Issue No. :  10

Year :  2011

Pages :   1578-1581

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis, Spectroscopic, Thermal Characterization and Biological Activity of (E)-4-(4-Methoxybenzylideneamino)-N-(5-Methylisoxazol-3-Yl) Benzenesulfonamide and Its Copper Complexes



Address:   M. Elnawawy, R.S. Farag, I.A. Sbbah and A.M. Abuyamine
Faculty of Science Al-Azhar University, Cairo, Egypt.
*Corresponding Author
DOI No:

ABSTRACT:
A Schiff base (E)-4-(4-methoxybenzylideneamino)-N-(5-methylis-oxazol-3-yl) benzene-sulfonamide (C18H17N3O4S), and its copper complex were synthesized and the structures elucidated in the bases of elemental analysis, 1HNMR, UV–VIS, IR, Mass spectroscopy, magnetic susceptibility, thermal analysis and conductance measurements. The studies indicate an octahedral structure for the complexes with the (C22H27N3O10SCu) formula. The I.R. spectra suggest that the ligand acts as a tridentate (NNO) donor. Also, the biological activity of the Schiff base and its Cu complex are biologically active.
KEYWORDS:
sulphamethoxazole, Schiff base, copper complex , antibacterial and antifungal activities.
Cite:
M. Elnawawy, R.S. Farag, I.A. Sbbah, A.M. Abuyamine. Synthesis, Spectroscopic, Thermal Characterization and Biological Activity of (E)-4-(4-Methoxybenzylideneamino)-N-(5-Methylisoxazol-3-Yl) Benzenesulfonamide and Its Copper Complexes. Asian J. Research Chem. 4(10): Oct., 2011; Page 1578-1581.
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