Journal :   Asian Journal of Research in Chemistry

Volume No. :   4

Issue No. :  12

Year :  2011

Pages :   1807-1811

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Pharmacological and Synthetic Profile of 1, 2, 4-Triazoles

Address:   Nachiket S. Dighe1*, Ravindra B. Saudagar2, Ramesh S. Kalkotwar3 and D.A. Jain4
1Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Loni, MS, India-413736.
2Department of Pharmaceutical Chemistry, R.G.Sapkal College of Pharmacy, Nashik, M.S. India.
3Department of pharmaceutical Chemistry, S.N.D. College of Pharmacy, Yeola, Dist-Nashik, MS, India.
4Department of Pharmaceutical Sciences and Research, Bhagwant University, Ajmer, Rajasthan, India
*Corresponding Author

Triazole is a five membered heterocyclic system consisting of two carbon atoms and three nitrogen atoms shows wide range of biological activities. Triazoles can be synthesized using Einhorn-Brunner reaction or the Pellizzari reaction from acyl hydrazides. Triazoles posses wide spectrum of biological activities like including antibacterial, antifungal, antiviral, anti-inflammatory, anticonvulsant, antidepressant, antihypertensive, analgesic, and hypoglycemic properties. The present reviews attempted to gather the various developments in synthesis and biological activities of triazole derivatives.
1, 2, 4-Triazole, Pharmacological activity, SAR, Total synthesis.
Nachiket S. Dighe, Ravindra B. Saudagar, Ramesh S. Kalkotwar, D.A. Jain. Pharmacological and Synthetic Profile of 1, 2, 4-Triazoles. Asian J. Research Chem. 4(12): Dec., 2011; Page 1807-1811.
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