Journal :   Asian Journal of Research in Chemistry

Volume No. :   4

Issue No. :  12

Year :  2011

Pages :   1818-1824

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Multi-Component Reaction and Their Application in Drug Discovery

Address:   Poonam R. Faldu1*, Sandip K. Dadhaniya2, Chirag J.Patel1 and G. Vidyasagar1
1 Veerayatan Institute of Pharmacy, Mandvi- Kutch, Gujarat
2R.B. Patel Mahila Pharmacy College, Atkot, Gujarat.
*Corresponding Author

Multicomponent reactions (MCRs) provide a powerful tool towards the one-pot synthesis of diverse and complex compounds on the one hand and small and ‘drug-like’ heterocycles on the other hand. No other single synthesis technology enables chemists to search such large chemical spaces as provided by MCRs. This review describes various three component and four component reaction example and recent advances in the application of isocyanide-based multicomponent reactions (IMCRs) in drug discovery.
Multicomponent reaction, Three component reaction, Four component reaction, Application, Isocyanide based reaction.
Poonam R. Faldu, Sandip K. Dadhaniya, Chirag J.Patel, G. Vidyasagar. Multi-Component Reaction and Their Application in Drug Discovery. Asian J. Research Chem. 4(12): Dec., 2011; Page 1818-1824.
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