Journal :   Asian Journal of Research in Chemistry

Volume No. :   4

Issue No. :  2

Year :  2011

Pages :   289-292

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Green Synthesis of Isoxazolidines: One Pot Facile Cycloaddition Reactions of Novel N-Phenyl-α-Amino Nitrone in Water



Address:   Bhaskar Chakraborty* and Neelam Rai
Organic Chemistry Laboratory, Sikkim Government College, Gangtok, Sikkim 737 102, India
*Corresponding Author
DOI No:

ABSTRACT:
Novel N-phenyl-a-amino nitrone has been synthesized from formamide and one pot facile 1,3-Dipolar cycloaddition reactions of the nitrone have been studied in water at room temperature in the stereoselective synthesis of novel isoxazolidine derivatives. Significant rate acceleration, changes in stereoselectivity and high yield of these reactions are observed in water compared to organic solvents.
KEYWORDS:
N-phenyl-α-amino nitrone, cycloaddition reaction, stereoselectivity, aqueous phase.
Cite:
Bhaskar Chakraborty, Neelam Rai. Green Synthesis of Isoxazolidines: One Pot Facile Cycloaddition Reactions of Novel N-Phenyl-α-Amino Nitrone in Water. Asian J. Research Chem. 4(2): February 2011; Page 289-292.
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