Journal :   Asian Journal of Research in Chemistry

Volume No. :   4

Issue No. :  2

Year :  2011

Pages :   316-321

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis of Some New 3-(4-Phthalimidophenyl)-5-(Substituted Phenyl) 4- Isoxazoline Derivatives with Analgesic and Anti-Inflammatory Activities.



Address:   Deepak Lande*, Meenakshi Deodhar, Ashok Bhosle and Ganesh Bhawal
Dep. of Pharmaceutical Chemistry, SGRS College of Pharmacy, Saswad, Pune, Maharashtra 412301, India
*Corresponding Author
DOI No:

ABSTRACT:
The derivatives of 3-(4-phthalimidophenyl)-5-(substituted-phenyl)-4-isoxazoline were synthesized, which were screened for their analgesic and anti-inflammatory activity in test animals. The analgesic activity of all compounds were found to be higher than their anti-inflammatory activity, Compounds 3b, 3e, 3h and 3l were found to be more active among the synthesized compounds.
KEYWORDS:
Thalidomide, Isoxazoline, Anti-inflammatory, Hydroxylamine hydrochloride.
Cite:
Deepak Lande, Meenakshi Deodhar, Ashok Bhosle, Ganesh Bhawal. Synthesis of Some New 3-(4-Phthalimidophenyl)-5-(Substituted Phenyl) 4- Isoxazoline Derivatives with Analgesic and Anti-Inflammatory Activities. Asian J. Research Chem. 4(2): February 2011; Page 316-321.
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