Journal :   Asian Journal of Research in Chemistry

Volume No. :   4

Issue No. :  4

Year :  2011

Pages :   560-566

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Theoretical Study of Geometry of Quinazoline Derivatives and Their Antibacterial Activities



Address:   Ramandeep Kaur, Monika Bansal and Balbir Kaur*
Department of Chemistry, Punjabi University, Patiala 147002, Punjab, India
*Corresponding Author
DOI No:

ABSTRACT:
Quinazolines are a pharmacologically very attractive class of compounds. In the preliminary communication, 4-substituted phenyl-3,4,5,6-tetrahydrobenzo[h]quinazoline-2(1H)-thiones and their S-alkyl/aralkyl derivatives were synthesized. Through the Gaussian 03 studies, the expected stereochemistry of the synthesized compounds was checked. Also, the compounds were tested for antibacterial activities against Staphylococcus aureus, Pseudomonas fluorescence.
KEYWORDS:
Quinazolines, Gaussian studies, Stereochemistry, Antibacterial activities.
Cite:
Ramandeep Kaur, Monika Bansal, Balbir Kaur. Theoretical Study of Geometry of Quinazoline Derivatives and Their Antibacterial Activities. Asian J. Research Chem. 4(4): April 2011; Page 560-566.
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