Journal :   Asian Journal of Research in Chemistry

Volume No. :   4

Issue No. :  5

Year :  2011

Pages :   754-756

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Spectrophotometric Method for Estimation of Efavirenz from Tablet Formulation

Address:   Gurav Suhas B1*, Dev Prakash1, Deshpande Anant N.2, Walsangikar Sandeep D.3
1Bharthi College of Pharmacy, Bharthinagara, K.M. Doodi -571 422, K.S. India
2Dyanand College of Pharmacy, Latur, M.S. India
3Shree Santkrupa College of Pharmacy, Ghogaon, Karad-411 110, M. S. India
*Corresponding Author

A simple, sensitive and accurate spectrophotometric method was developed in ultraviolet region for the estimation of Efavirenz (EFA) in pure drug, pharmaceutical formulation. Linear response obtained was in the concentration range of 5-40 µg/ml with correlation coefficient of 0.9993 in solvent. Excellent recovery proved that the method was sufficiently accurate. There is no interference from any common pharmaceutical additives and diluents. Results of the analysis were validated by recovery studies according to ICH Q2B guidelines.
Efavirenz, UV- Spectrophotometry, recovery, accuracy.
Gurav Suhas B, Dev Prakash, Deshpande Anant N., Walsangikar Sandeep D.. Spectrophotometric Method for Estimation of Efavirenz from Tablet Formulation. Asian J. Research Chem. 4(5): May, 2011; Page 754-756.
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