Journal :   Asian Journal of Research in Chemistry

Volume No. :   4

Issue No. :  5

Year :  2011

Pages :   685-694

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Biodiversity of Oxazolone Derivatives in Medicinal Chemistry: A Review



Address:   Suman Bala*, Minaxi Saini, Sunil Kamboj, Goldie Uppal and Ashok Kumar
M.M. College of Pharmacy, Maharishi Markandeshwar University, Mullana, Ambala, Haryana-133203
*Corresponding Author
DOI No:

ABSTRACT:
There has been keen interest in the development of novel compounds with antimicrobial, analgesic, antiinflammatory, anticancer, anti-HIV, antiangiogenic, anticonvulsant, antitumor, antagonistic and cardiotonic activity. Oxazolone, a five membered heterocyclic nucleus is a versatile lead compound for designing potent medicinally active agents. This review represents the diverse biological applications of oxazolone and their excellent performance as a substrate in the synthesis of various heterocyclic bioactive compounds, which fascinates the medicinal chemists to pursue research on this nucleus.
KEYWORDS:
Erlenmeyer reaction, Diels-Alder reaction, Azlactone, Antimicrobial activity.
Cite:
Suman Bala, Minaxi Saini, Sunil Kamboj, Goldie Uppal, Ashok Kumar. Biodiversity of Oxazolone Derivatives in Medicinal Chemistry: A Review. Asian J. Research Chem. 4(5): May, 2011; Page-685-694.
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