Journal :   Asian Journal of Research in Chemistry

Volume No. :   4

Issue No. :  5

Year :  2011

Pages :   805-809

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Studies on Inclusion Complexes of Nitrosubstituted Indole Derivatives



Address:   Sunakar Panda1* and Jagat Krushna Tripathy2
PG Department of Chemistry Berhampur University, Bhanja Bihar-760007, Odisha India
*Corresponding Author
DOI No:

ABSTRACT:
A number of [arylidenamino]-1,3,4-thiadiazino[6,5b]indoles with nitro groups have been synthesized in their purest form starting from indole-2,3-dione and using ortho, meta and para nitro benzaldehyde. In order to increase the solubility of these compounds in polar medium, their inclusion complexes have been prepared with ß-cyclodextrin. The formation of compounds and their inclusion complexes have been ascertained from elemental analysis and study of spectral characteristics. The stability of inclusion complexes is known from the study of thermodynamics parameters like change in free energy, change in enthalpy and change in entropy. The results clearly suggest existence of noncovalent intermolecular forces in between the guest compounds and host ß-cyclodextrin during inclusion complex formation.
KEYWORDS:
Substitutedindole, Nitrobenzaldehyde, β-Cyclodextrin, Inclusion complex.
Cite:
Sunakar Panda, Jagat Krushna Tripathy. Studies on Inclusion Complexes of Nitrosubstituted Indole Derivatives. Asian J. Research Chem. 4(5): May, 2011; Page 805-809.
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