Journal :   Asian Journal of Research in Chemistry

Volume No. :   4

Issue No. :  5

Year :  2011

Pages :   715-718

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Spectrophotometric Determination of Naproxen Sodium with Bromocresol Green and Bromothymol Blue as Chromogenic Reagents.



Address:   N. V. S. Venugopal*, V. Nageswara Raoand and B. Sumalatha
Department of Chemistry, G.I.T, Gitam University, Rushikonda, Visakhpatnam-530045, A.P, India.
*Corresponding Author
DOI No:

ABSTRACT:
Spectrophotometric method has been proposed for the determination of Naproxen sodium (a non steroidal anti-inflammatory drug). The method is based on the formation of a 1:1 ion pair with Bromocresol green and Bromothymol blue in the PH range over 3.2-4.4 to give blue colored chromogen. Under the proposed optimum condition, Beer’s law was obeyed in the concentration range of 0.01-5mg/10 mL. The procedures are characterized by its simplicity with accuracy and precision.
KEYWORDS:
Naproxen sodium; bromocresolgreen; bromothymol blue; spectrophotometry.
Cite:
N. V. S. Venugopal, V. Nageswara Raoand, B. Sumalatha. Spectrophotometric Determination of Naproxen Sodium with Bromocresol Green and Bromothymol Blue as Chromogenic Reagents. Asian J. Research Chem. 4(5): May, 2011; Page 715-718.
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