Journal :   Asian Journal of Research in Chemistry

Volume No. :   4

Issue No. :  7

Year :  2011

Pages :   1100-1102

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Absorption Correction Method for Estimation of Amlodipine Besylate and Olmesartan Medoxomil in Combined Tablet Dosage Form.



Address:   K. Anand Babu1*, B. Jayakar1 and G. Vinoth Kumar2
1Vinayaka Mission College of Pharmacy, Salem-636008, Tamilnadu, India,
2SRM College of Pharmacy, Kattankulathur-603203, Tamilnadu, India.
*Corresponding Author
DOI No:

ABSTRACT:
A new, simple, accurate and sensitive UV - spectrophotometric absorption correction method has been developed for simultaneous determination of amlodipine besylate and olmesartan medoxomil in combined tablet dosage form. Methanol and distilled water were used as solvents. The wavelengths selected for the analysis were 363nm and 258 nm for amlodipine besylate and olmesartan medoxomil, respectively. Beer’s law obeyed the concentration range of 1.25–6.25 µg/ ml and 5 – 25 µg/ml for amlodipine besylate and olmesartan medoxomil respectively. The method was validated stastically.
KEYWORDS:
Amlodipine Besylate, Olmesartan medoxomil, Absorption correction method, ICH guidelines.
Cite:
K. Anand Babu, B. Jayakar, G. Vinoth Kumar. Absorption Correction Method for Estimation of Amlodipine Besylate and Olmesartan Medoxomil in Combined Tablet Dosage Form. Asian J. Research Chem. 4(7): July, 2011; Page 1100-1102.
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