Journal :   Asian Journal of Research in Chemistry

Volume No. :   4

Issue No. :  7

Year :  2011

Pages :   1161-1163

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Spectrophotometric Determination of Mosapride Citrate in Pharmaceutical Formulations



Address:   M. Purushotham Reddy1, P. Ravindra Reddy2 and N. Rami Reddy3
1Department of Chemistry, Government College for Men, Kurnool-518002, India
2Department of Chemistry, S. K. University, Anantapur-515003, India
3Department of Chemistry, S.B.S.Y.M. Degree College, Kurnool-518218, India
*Corresponding Author
DOI No:

ABSTRACT:
A simple spectrophotometric method has been developed for the estimation of mosapride in tablet formulations. The method is based on the formation of a orange coloured azo product by the diazotization of mosapride followed by a coupling reaction with resorcinol. The absorbance of orange coloured solution is measured at 470 nm against reagent blank. Beer’s law is obeyed in the concentration of 20-100 ?g/ml of drug. The method is successfully employed for the determination of mosapride in tablets formulations.
KEYWORDS:
Spectrophotometry, mosapride citrate, resorcinol, diazotization Formulations.
Cite:
M. Purushotham Reddy, P. Ravindra Reddy, N. Rami Reddy.Spectrophotometric Determination of Mosapride Citrate in Pharmaceutical Formulations. Asian J. Research Chem. 4(7): July, 2011; Page 1161-1163.
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