Journal :   Asian Journal of Research in Chemistry

Volume No. :   4

Issue No. :  9

Year :  2011

Pages :   1485-1488

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis and Evaluation of antioxidant and anti-inflammatory activity of Conjugates of Amino Acids with N-Aroyl- N, N′-Dicyclohexyl Urea



Address:   Shakti Prasanna Sahoo1*, Bharat Bhusan Subudhi 2 and Rachana Swain1
1A.K.R.G. College of Pharmacy, Nallajerla, West Godavari, Andhra Pradesh,-534112. India
2School of Pharmaceutical Sciences, Siksha O Anusandhan University, Bhubaneswar, Orissa, -751003. India
*Corresponding Author
DOI No:

ABSTRACT:
A series of 2-((2-3-benzoyl-1,3-dicyclohexylureido)-2-oxoethyl)amino)-3-(4hydroxyphenyl) propanoic acid (3a) and its analogs were synthesized from N,N'-Dicyclohexylcarbodiimide (DCC) by acetylating and finally condensing with amino acids to yield good antioxidant molecules which are showing the potency nearer to ascorbic acid and exploring their anti inflammatory activity.
KEYWORDS:
Amino acid, N-aroyl- N, N′-dicyclohexyl urea, Antioxidant, DPPH,
Cite:
Shakti Prasanna Sahoo, Bharat Bhusan Subudhi, Rachana Swain. Synthesis and Evaluation of antioxidant and anti-inflammatory activity of Conjugates of Amino Acids with N-Aroyl- N, N′-Dicyclohexyl Urea. Asian J. Research Chem. 4(9): Sept, 2011; Page 1485-1488.
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