Journal :   Asian Journal of Research in Chemistry

Volume No. :   5

Issue No. :  1

Year :  2012

Pages :   14-17

ISSN Print :  0974-4169

ISSN Online :  0974-4150


Registration

Allready Registrered
Click to Login

Simple and Rapid Spectrofluorometric Fingerprint Development of Quinine in Unani Formulation



Address:   Shiv Shankar Shukla, Swarnlata Saraf, Shailendra Saraf*
University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur
(Chhattisgarh)- India 492010
Corresponding author
DOI No:

ABSTRACT:
A simple, precise and accurate spectrofluorometric method has been established for quantitative determination of quinine. Conditions were also optimized for best possible extraction of quinine via varying concentrations of different solvents for maximum recovery of quinine at excitation wavelength 372 nm and emission wavelength 456 nm. Methanol found to be best for highest possible recovery of target analyte quinine. The linear range of 1.0– 7.0 µg/mL was obtained for quinine. The detection limit was 0.1768 and quantitation limit was found to be 0.5411for quinine. The recovery of the quinine was found to be 97.35–99.85 %. The proposed method was used for the determination of quinine alkaloids in pharmaceuticals and herbal formulations with satisfactory result.
KEYWORDS:
Unani medicine, validation, spectrofluorometer, quinine.
Cite:
Shiv Shankar Shukla, Swarnlata Saraf, Shailendra Saraf. Simple and Rapid Spectrofluorometric Fingerprint Development of Quinine in Unani Formulation. Asian J. Research Chem. 5(1): January 2012; Page 14-17.
[View HTML]      [View PDF]



Visitor's No. :   106632