Journal :   Asian Journal of Research in Chemistry

Volume No. :   5

Issue No. :  10

Year :  2012

Pages :   1207-1209

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Visible Colourimetric Estimation of Moprolol in Bulk and Mouth Dissolving Tablet Dosage Forms



Address:   Rekha Rajeevkumar1*, Dr. S. Anbazhagan1 and P. Rajeev Kumar2
1Department of Pharmaceutical Analysis, Karuna College of Pharmacy, Thirumittacode, Palakkad (Kerala) India
2Department of Pharmaceutics, Karuna College of Pharmacy, Thirumittacode, Palakkad (Kerala) India
*Corresponding Author
DOI No:

ABSTRACT:
Simple and sensitive visible spectrophotometric method has been developed for the determination of Moprolol in mouth dissolving tablet dosage forms. The Method is based on the formation of colored species on binding of Moprolol with sodium carbonate, sodium hydroxide followed by Folin – Ciocaltaeu reagent (F/C) to produce blue colored chromogen with absorption maximum at 520 nm and Beer’s law is obeyed in the concentration range of 5-25µg/ml. The developed method was found to be precise and accurate. The results obtained are statistically validated and found to be reproducible.
KEYWORDS:
Validation, Moprolol, Dimethylformamide (DMF), Spectrophotometric, Folin – Ciocaltaeu reagent (F/C).
Cite:
Rekha Rajeevkumar, S. Anbazhagan, P. Rajeev Kumar. Visible Colourimetric Estimation of Moprolol in Bulk and Mouth Dissolving Tablet Dosage Forms. Asian J. Research Chem. 5(10): October, 2012; Page 1207-1209.
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