Journal :   Asian Journal of Research in Chemistry

Volume No. :   5

Issue No. :  11

Year :  2012

Pages :   1399-1404

ISSN Print :  0974-4169

ISSN Online :  0974-4150


Registration

Allready Registrered
Click to Login

Synthesis, Characterization and Antimicrobial Activity of Some Schiff Bases of 2-Amino-N-(o-Fluorophenylcarboxamido)-4-(p-Methoxyphenyl) Thiophenes



Address:   Shivaji Bhattacharjee*, Monica Arrora, J. Saravanan, S. Mohan
Dept. of Pharmaceutical Chemistry, PES College of Pharmacy, Bangalore --560050, India
*Corresponding Author
DOI No:

ABSTRACT:
The novel 2-amino-N-(o-fluorophenylcarboxamido)-4-(p-methoxyphenyl)-thiophene [I] was synthesized by using a pioneer method and the parent compound [I] was reacted with different substituted aryl aldehydes to obtain a series of title compounds [I a-l]. All the new title compounds were characterized by spectral data and were screened for Antimicrobial activity. In conclusion, it can be inferred that the electron donating groups on the phenyl ring at R of the title compounds influenced the Antimicrobial activity.
KEYWORDS:
Synthesis, Thiophene, Schiff Base, Characterization, Antimicrobial activity.
Cite:
Shivaji Bhattacharjee, Monica Arrora, J. Saravanan, S. Moha. Synthesis, Characterization and Antimicrobial Activity of Some Schiff Bases of 2-Amino-N-(o-Fluorophenylcarboxamido)-4-(p-Methoxyphenyl) Thiophenes. Asian J. Research Chem. 5(11): Nov., 2012; Page 1399-1404.
[View HTML]      [View PDF]



Visitor's No. :   112359