Journal :   Asian Journal of Research in Chemistry

Volume No. :   5

Issue No. :  3

Year :  2012

Pages :   401-404

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Efficient Synthesis of Novel Pyrazolo thiazole derivatives and its Microbial Studies



Address:   Sivagurunathan K., S. Raja Mohamed Kamil*
Department of Chemistry, Islamiah College, Vaniyambadi - 635 751, Tamil Nadu, India.
*Corresponding Author
DOI No:

ABSTRACT:
Novel pyrazolo thiazole derivatives were synthesized by thioamide treated with various a-haloketones in ethanol. The structures of the newly synthesized compounds are characterized by 1HNMR, 13C NMR, LC-MS and screened for their antibacterial activity against Escherichia coli (ATTC-25992), Staphylococcus aureus (ATTC-25923), Pseudomonas aeruginosa (ATTC-27853) and Klebsiella pneumonia.
KEYWORDS:
Tert-butyl 6, 7-dihydro-1-methyl-3-thiocarbamoyl-1-H-pyrazolo [4, 3-c] pyridine-5-(4H)carboxylate, Synthesis, Antibacterial activity.
Cite:
Sivagurunathan K., S. Raja Mohamed Kamil. Efficient Synthesis of Novel Pyrazolo thiazole derivatives and its Microbial Studies. Asian J. Research Chem. 5(3): March 2012; Page 401-404.
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