Journal :   Asian Journal of Research in Chemistry

Volume No. :   5

Issue No. :  3

Year :  2012

Pages :   414-417

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis and evaluation of antibacterial activity of some Benzopyran-4-one derivatives

Address:   Sukhen Som1* and K.N. Jayaveera2
1Department of Pharma. Chemistry, M.M.U College of Pharmacy, K. K. Doddi, Ramanagara- 571511Karnataka
2Department of Chemistry, Jawaharlal Nehru Technological University Anantapur, Anantapur, Andhra Pradesh
*Corresponding Author

In view of the general observations that Benzopyrone derivatives are associated with antibacterial, anti-inflammatory, anticancer, antihepatotoxic activity etc. it was our interest to prepare different substituted Benzopyrone derivatives and evaluate them for their antibacterial activity.A series of substituted benzopyran-4-one derivatives were synthesized through various steps starting from 2-benzoyloxy-4-substituted acetophenone. The structures of the synthesized compounds were confirmed by their spectral and analytical data. Out of all synthesized compounds 6a and 6b and compounds 6f, 6i and 6k showed maximum activity against E.coli and S.aureus.
Antibacterial activity, Acylation, Bromination.
Sukhen Som, K.N. Jayaveera. Synthesis and evaluation of antibacterial activity of some Benzopyran-4-one derivatives. Asian J. Research Chem. 5(3): March 2012; Page 414-417.
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