Registered User Login
Asian Journal of Research in Chemistry
ISSN: 0974-4150(Online), 0974-4169(Print)
Home
|
About AJRC
|
Current Issue
|
Archives
|
Editorial Board
|
Instructions
|
Paper Submission
|
News & Conferences
|
Subscription
|
Corrigendum
|
Contact Us
Journal :
Asian Journal of Research in Chemistry
Volume No. :
5
Issue No. :
3
Year :
2012
Pages :
329-335
ISSN Print :
0974-4169
ISSN Online :
0974-4150
Registration
Allready Registrered
Click to Login
Synthesis and characterization of novel impurities in Paroxetine Hydrochloride hemihydrate and adopting QbD principles to built in quality in process of final drug substance
Ramesh Yamgar
,
Sudhir Sawant
sawantsudhir@hotmail.com
Address:
Ramesh Yamgar and Sudhir Sawant*
P. G. Dept of Chemistry, Govt. of Maharashtra’s Ismail Yusuf College of Arts, Science and Commerce, Jogeshwari (East), Mumbai 400 060 INDIA
*Corresponding Author
DOI No:
ABSTRACT:
Synthesis of two novel impurities in the manufacturing process of Paroxetine.HCl. ½H2O is described. They were characterized by spectroscopic techniques like 1HNMR, 13CNMR and MS. Synthesis and reaction mechanism is also explained in details.
KEYWORDS:
Impurity synthesis and characterization, QbD, Environmental protection.
Cite:
Ramesh Yamgar, Sudhir Sawant. Synthesis and characterization of novel impurities in Paroxetine Hydrochloride hemihydrate and adopting QbD principles to built in quality in process of final drug substance. Asian J. Research Chem. 5(3): March 2012; Page 329-335.
[View HTML]
[View PDF]
Visitor's No. :
277113