Journal :   Asian Journal of Research in Chemistry

Volume No. :   5

Issue No. :  5

Year :  2012

Pages :   659-662

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Microwave Induced Synthesis and Antimicrobial Activity of Some Sodium 4- [Diphenyl-4, 41- Diylbis (Diazene -2, 1- Diyl) Bis (1- Aminonaphtholene -4- Sulfonate)] Derivatives



Address:   Nirupma Jadon1*, Sadhana Singh1 and Kuldeep Singh Jadon2
1Department of Chemistry, SBP Govt. College, Dungarpur (Raj.)
2Department of Plant Pathology, RCA Udaipur (Raj.) India 313001
*Corresponding Author
DOI No:

ABSTRACT:
The title compound were synthesized by the diazotized tetrazotised (bis-diazotised) benzidine (1) coupled with naphthionic acid solution under microwave irradiation (MW)1 to get sodium 4 –[diphenyl-4,41 diylbis (diazehe-2, 1- diyl) bis (1- aminonaphthalene-4-sulfonate)] (2). Which then treated with conc. Sulphuric acid, Benzoyl chloride and NaOH, Sodium bisulphite and NaOH to give derivatives sodium 4- [diphenyl – 4, 41- diylbis (diazene-2, 1 - diyl) bis (6- sulfo-1- amino naphthalene sulfonate)] (2a), Sodium 4- [diphenyl -4, 41-diylibis (diazene-2,1-diyl) bis (N-benzoyl) naphthalene sulfonate] (2b), Sodium 4- [diphenyl -4, 41 diylbis (diazene -2,1 -diyl) bis (1- hydroxynaphthalene -4- sulfonate)] (2C), under microwave irradiation. Newly synthesized compounds were confirmed by IR and mass analysis. The synthesized compounds were screened for their antimicrobial activity in vitro.
KEYWORDS:
Microwave irradiation, solvent free path, one pot synthesis, some sodium 4- [diphenyl – 4, 41- diylbis (diazene-2, 1 - diyl) bis (1- aminonaphthalene -4- sulfonate)] derivatives, antimicrobial activity.
Cite:
Nirupma Jadon, Sadhana Singh, Kuldeep Singh Jadon. Microwave Induced Synthesis and Antimicrobial Activity of Some Sodium 4- [Diphenyl-4, 41- Diylbis (Diazene -2, 1- Diyl) Bis (1- Aminonaphtholene -4- Sulfonate)] Derivatives. Asian J. Research Chem. 5(5): May 2012; Page 659-662.
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