Journal :   Asian Journal of Research in Chemistry

Volume No. :   5

Issue No. :  6

Year :  2012

Pages :   733-737

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Qualitative and Pharmacological Evaluation of Root Extracts of Withania somnifera against Human and Plant Pathogens



Address:   Dr. Premlata Singariya1*, Prof. Padma Kumar1 and Dr. Krishan Kumar Mourya2
1Dr. D.S. Kothari Post Doctoral Fellow, Laboratory of Tissue Culture and Secondary Metabolites, Department of Botany, University of Rajasthan, Jaipur- 302004
2Veterinary Officer and In-Charge, Ist Gr. Govt. Veterinary Hospital, Pahari (Bharatpur) Rajasthan.
*Corresponding Author
DOI No:

ABSTRACT:
AIMS: The aim of present study is to investigate the antimicrobial activity of root extracts of Withania somnifera, in order to use it as a possible source for new antimicrobial substances against important human and plant pathogens. SETTINGS AND DESIGN: The roots of Withania somnifera were evaluated against medically important bacteria viz. Proteus merabilis, Klebsiella pnemoniae, Agerobacterium tumefaciens (plant pathogen) and one fungi Aspergillus niger. METHODS AND MATERIAL: The dried and powdered roots of W. somnifera were successively extracted with a series of non polar to polar solvents using soxhlet assembly. The antimicrobial assay was done by both disc diffusion and serial dilution methods. RESULTS: Glacial acetic acid extract and benzene extract of W. somnifera show highest activity against A. tumefaciens (plant pathogen) to varying degrees, by most of the extracts.
KEYWORDS:
Agerobacterium tumefaciens, antibacterial, antifungal, Aspergillus niger, Klebsiella pnemoniae and Proteus merabilis.
Cite:
Premlata Singariya, Padma Kumar, Krishan Kumar Mourya. Qualitative and Pharmacological Evaluation of Root Extracts of Withania somnifera against Human and Plant Pathogens. Asian J. Research Chem. 5(6): June, 2012; Page 733-737.
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